diff --git a/moto/ec2/models.py b/moto/ec2/models.py
index 91b98cca6..63f0a3123 100644
--- a/moto/ec2/models.py
+++ b/moto/ec2/models.py
@@ -542,6 +542,14 @@ class InstanceBackend(object):
                 instances.append(instance)
         return instances
 
+    def all_running_instances(self):
+        instances = []
+        for reservation in self.all_reservations():
+            for instance in reservation.instances:
+                if instance.state_code == 16:
+                    instances.append(instance)
+        return instances
+
     def get_multi_instances_by_id(self, instance_ids):
         """
         :param instance_ids: A string list with instance ids
diff --git a/moto/ec2/responses/instances.py b/moto/ec2/responses/instances.py
index 49050f9d6..b1ccc7e12 100644
--- a/moto/ec2/responses/instances.py
+++ b/moto/ec2/responses/instances.py
@@ -4,7 +4,7 @@ from jinja2 import Template
 from moto.core.responses import BaseResponse
 from moto.core.utils import camelcase_to_underscores
 from moto.ec2.utils import instance_ids_from_querystring, filters_from_querystring, filter_reservations, \
-    dict_from_querystring
+    dict_from_querystring, optional_from_querystring
 
 
 class InstanceResponse(BaseResponse):
@@ -69,11 +69,15 @@ class InstanceResponse(BaseResponse):
 
     def describe_instance_status(self):
         instance_ids = instance_ids_from_querystring(self.querystring)
+        include_all_instances = optional_from_querystring('IncludeAllInstances',
+                                                        self.querystring) == 'true'
 
         if instance_ids:
             instances = self.ec2_backend.get_multi_instances_by_id(instance_ids)
-        else:
+        elif include_all_instances:
             instances = self.ec2_backend.all_instances()
+        else:
+            instances = self.ec2_backend.all_running_instances()
 
         template = Template(EC2_INSTANCE_STATUS)
         return template.render(instances=instances)
@@ -512,27 +516,36 @@ EC2_INSTANCE_STATUS = """<?xml version="1.0" encoding="UTF-8"?>
             <instanceId>{{ instance.id }}</instanceId>
             <availabilityZone>us-east-1d</availabilityZone>
             <instanceState>
-                <code>16</code>
-                <name>running</name>
+                <code>{{ instance.state_code }}</code>
+                <name>{{ instance.state }}</name>
             </instanceState>
-            <systemStatus>
-                <status>ok</status>
-                <details>
-                    <item>
-                        <name>reachability</name>
-                        <status>passed</status>
-                    </item>
-                </details>
-            </systemStatus>
-            <instanceStatus>
-                <status>ok</status>
-                <details>
-                    <item>
-                        <name>reachability</name>
-                        <status>passed</status>
-                    </item>
-                </details>
-            </instanceStatus>
+            {% if instance.state_code == 16 %}
+              <systemStatus>
+                  <status>ok</status>
+                  <details>
+                      <item>
+                          <name>reachability</name>
+                          <status>passed</status>
+                      </item>
+                  </details>
+              </systemStatus>
+              <instanceStatus>
+                  <status>ok</status>
+                  <details>
+                      <item>
+                          <name>reachability</name>
+                          <status>passed</status>
+                      </item>
+                  </details>
+              </instanceStatus>
+            {% else %}
+              <systemStatus>
+                  <status>not-applicable</status>
+              </systemStatus>
+              <instanceStatus>
+                  <status>not-applicable</status>
+              </instanceStatus>
+            {% endif %}
         </item>
       {% endfor %}
     </instanceStatusSet>
diff --git a/tests/test_ec2/test_instances.py b/tests/test_ec2/test_instances.py
index 98740a8ae..150544b49 100644
--- a/tests/test_ec2/test_instances.py
+++ b/tests/test_ec2/test_instances.py
@@ -516,3 +516,29 @@ def test_describe_instance_status_with_instance_filter():
     cm.exception.code.should.equal('InvalidInstanceID.NotFound')
     cm.exception.status.should.equal(400)
     cm.exception.request_id.should_not.be.none
+
+@requires_boto_gte("2.32.0")
+@mock_ec2
+def test_describe_instance_status_with_non_running_instances():
+    conn = boto.connect_ec2('the_key', 'the_secret')
+    reservation = conn.run_instances('ami-1234abcd', min_count=3)
+    instance1, instance2, instance3 = reservation.instances
+    instance1.stop()
+    instance2.terminate()
+
+    all_running_status = conn.get_all_instance_status()
+    all_running_status.should.have.length_of(1)
+    all_running_status[0].id.should.equal(instance3.id)
+    all_running_status[0].state_name.should.equal('running')
+
+    all_status = conn.get_all_instance_status(include_all_instances=True)
+    all_status.should.have.length_of(3)
+
+    status1 = next((s for s in all_status if s.id == instance1.id), None)
+    status1.state_name.should.equal('stopped')
+
+    status2 = next((s for s in all_status if s.id == instance2.id), None)
+    status2.state_name.should.equal('terminated')
+
+    status3 = next((s for s in all_status if s.id == instance3.id), None)
+    status3.state_name.should.equal('running')