diff --git a/moto/rds/models.py b/moto/rds/models.py
index 9a670c2fd..a89db9e2e 100644
--- a/moto/rds/models.py
+++ b/moto/rds/models.py
@@ -1950,6 +1950,9 @@ class RDSBackend(BaseBackend):
 
     def describe_db_clusters(self, cluster_identifier):
         if cluster_identifier:
+            # ARN to identifier
+            # arn:aws:rds:eu-north-1:123456789012:cluster:cluster --> cluster-id
+            cluster_identifier = cluster_identifier.split(":")[-1]
             if cluster_identifier in self.clusters:
                 return [self.clusters[cluster_identifier]]
             if cluster_identifier in self.neptune.clusters:
diff --git a/tests/test_rds/test_rds_clusters.py b/tests/test_rds/test_rds_clusters.py
index e78ffb9ad..d5e1be474 100644
--- a/tests/test_rds/test_rds_clusters.py
+++ b/tests/test_rds/test_rds_clusters.py
@@ -250,12 +250,12 @@ def test_describe_db_cluster_after_creation():
         MasterUserPassword="hunter2_",
     )
 
-    client.create_db_cluster(
+    cluster_arn = client.create_db_cluster(
         DBClusterIdentifier="cluster-id2",
         Engine="aurora",
         MasterUsername="root",
         MasterUserPassword="hunter2_",
-    )
+    )["DBCluster"]["DBClusterArn"]
 
     client.describe_db_clusters()["DBClusters"].should.have.length_of(2)
 
@@ -263,6 +263,10 @@ def test_describe_db_cluster_after_creation():
         "DBClusters"
     ].should.have.length_of(1)
 
+    client.describe_db_clusters(DBClusterIdentifier=cluster_arn)[
+        "DBClusters"
+    ].should.have.length_of(1)
+
 
 @mock_rds
 def test_delete_db_cluster():