diff --git a/moto/ec2/models.py b/moto/ec2/models.py
index 9c30cb119..1a5f0a21e 100644
--- a/moto/ec2/models.py
+++ b/moto/ec2/models.py
@@ -1817,12 +1817,12 @@ class RouteTableBackend(object):
 
 class Route(object):
     def __init__(self, route_table, destination_cidr_block, local=False,
-                 internet_gateway=None, instance=None, interface=None, vpc_pcx=None):
+                 gateway=None, instance=None, interface=None, vpc_pcx=None):
         self.id = generate_route_id(route_table.id, destination_cidr_block)
         self.route_table = route_table
         self.destination_cidr_block = destination_cidr_block
         self.local = local
-        self.internet_gateway = internet_gateway
+        self.gateway = gateway
         self.instance = instance
         self.interface = interface
         self.vpc_pcx = vpc_pcx
@@ -1861,8 +1861,15 @@ class RouteBackend(object):
         if interface_id:
             self.raise_not_implemented_error("CreateRoute to NetworkInterfaceId")
 
+        gateway = None
+        if gateway_id:
+            if EC2_RESOURCE_TO_PREFIX['vpn-gateway'] in gateway_id:
+                gateway = self.get_vpn_gateway(gateway_id)
+            elif EC2_RESOURCE_TO_PREFIX['internet-gateway'] in gateway_id:
+                gateway = self.get_internet_gateway(gateway_id)
+
         route = Route(route_table, destination_cidr_block, local=local,
-                      internet_gateway=self.get_internet_gateway(gateway_id) if gateway_id else None,
+                      gateway=gateway,
                       instance=self.get_instance(instance_id) if instance_id else None,
                       interface=None,
                       vpc_pcx=self.get_vpc_peering_connection(vpc_peering_connection_id) if vpc_peering_connection_id else None)
@@ -1879,7 +1886,13 @@ class RouteBackend(object):
         if interface_id:
             self.raise_not_implemented_error("ReplaceRoute to NetworkInterfaceId")
 
-        route.internet_gateway = self.get_internet_gateway(gateway_id) if gateway_id else None
+        route.gateway = None
+        if gateway_id:
+            if EC2_RESOURCE_TO_PREFIX['vpn-gateway'] in gateway_id:
+                route.gateway = self.get_vpn_gateway(gateway_id)
+            elif EC2_RESOURCE_TO_PREFIX['internet-gateway'] in gateway_id:
+                route.gateway = self.get_internet_gateway(gateway_id)
+
         route.instance = self.get_instance(instance_id) if instance_id else None
         route.interface = None
         route.vpc_pcx = self.get_vpc_peering_connection(vpc_peering_connection_id) if vpc_peering_connection_id else None
diff --git a/moto/ec2/responses/route_tables.py b/moto/ec2/responses/route_tables.py
index f583cbbfb..632c671a8 100644
--- a/moto/ec2/responses/route_tables.py
+++ b/moto/ec2/responses/route_tables.py
@@ -17,13 +17,13 @@ class RouteTables(BaseResponse):
         route_table_id = self.querystring.get('RouteTableId')[0]
         destination_cidr_block = self.querystring.get('DestinationCidrBlock')[0]
 
-        internet_gateway_id = optional_from_querystring('GatewayId', self.querystring)
+        gateway_id = optional_from_querystring('GatewayId', self.querystring)
         instance_id = optional_from_querystring('InstanceId', self.querystring)
         interface_id = optional_from_querystring('NetworkInterfaceId', self.querystring)
         pcx_id = optional_from_querystring('VpcPeeringConnectionId', self.querystring)
 
         self.ec2_backend.create_route(route_table_id, destination_cidr_block,
-            gateway_id=internet_gateway_id,
+            gateway_id=gateway_id,
             instance_id=instance_id,
             interface_id=interface_id,
             vpc_peering_connection_id=pcx_id)
@@ -67,13 +67,13 @@ class RouteTables(BaseResponse):
         route_table_id = self.querystring.get('RouteTableId')[0]
         destination_cidr_block = self.querystring.get('DestinationCidrBlock')[0]
 
-        internet_gateway_id = optional_from_querystring('GatewayId', self.querystring)
+        gateway_id = optional_from_querystring('GatewayId', self.querystring)
         instance_id = optional_from_querystring('InstanceId', self.querystring)
         interface_id = optional_from_querystring('NetworkInterfaceId', self.querystring)
         pcx_id = optional_from_querystring('VpcPeeringConnectionId', self.querystring)
 
         self.ec2_backend.replace_route(route_table_id, destination_cidr_block,
-            gateway_id=internet_gateway_id,
+            gateway_id=gateway_id,
             instance_id=instance_id,
             interface_id=interface_id,
             vpc_peering_connection_id=pcx_id)
@@ -152,8 +152,8 @@ DESCRIBE_ROUTE_TABLES_RESPONSE = """
                   <origin>CreateRouteTable</origin>
                   <state>active</state>
                 {% endif %}
-                {% if route.internet_gateway %}
-                  <gatewayId>{{ route.internet_gateway.id }}</gatewayId>
+                {% if route.gateway %}
+                  <gatewayId>{{ route.gateway.id }}</gatewayId>
                   <origin>CreateRoute</origin>
                   <state>active</state>
                 {% endif %}
diff --git a/tests/test_ec2/test_route_tables.py b/tests/test_ec2/test_route_tables.py
index e31d34125..38ccd09c8 100644
--- a/tests/test_ec2/test_route_tables.py
+++ b/tests/test_ec2/test_route_tables.py
@@ -419,6 +419,29 @@ def test_routes_vpc_peering_connection():
     new_route.destination_cidr_block.should.equal(ROUTE_CIDR)
 
 
+@requires_boto_gte("2.34.0")
+@mock_ec2
+def test_routes_vpn_gateway():
+
+    conn = boto.connect_vpc('the_key', 'the_secret')
+    vpc = conn.create_vpc("10.0.0.0/16")
+    main_route_table = conn.get_all_route_tables(filters={'association.main':'true','vpc-id':vpc.id})[0]
+    ROUTE_CIDR = "10.0.0.4/24"
+
+    vpn_gw = conn.create_vpn_gateway(type="ipsec.1")
+
+    conn.create_route(main_route_table.id, ROUTE_CIDR, gateway_id=vpn_gw.id)
+
+    main_route_table = conn.get_all_route_tables(main_route_table.id)[0]
+    new_routes = [route for route in main_route_table.routes if route.destination_cidr_block != vpc.cidr_block]
+    new_routes.should.have.length_of(1)
+
+    new_route = new_routes[0]
+    new_route.gateway_id.should.equal(vpn_gw.id)
+    new_route.instance_id.should.be.none
+    new_route.vpc_peering_connection_id.should.be.none
+
+
 @mock_ec2
 def test_network_acl_tagging():