diff --git a/moto/s3/responses.py b/moto/s3/responses.py
index eb21e6710..3a0df6987 100644
--- a/moto/s3/responses.py
+++ b/moto/s3/responses.py
@@ -1347,7 +1347,7 @@ class ResponseObject(_TemplateEnvironmentMixin, ActionAuthenticatorMixin):
                 max_parts=max_parts,
             )
             next_part_number_marker = parts[-1].name if parts else 0
-            is_truncated = parts and self.backend.is_truncated(
+            is_truncated = len(parts) != 0 and self.backend.is_truncated(
                 bucket_name, upload_id, next_part_number_marker
             )
 
diff --git a/tests/test_s3/test_s3_multipart.py b/tests/test_s3/test_s3_multipart.py
index b61ad0c66..38cb5c04c 100644
--- a/tests/test_s3/test_s3_multipart.py
+++ b/tests/test_s3/test_s3_multipart.py
@@ -107,6 +107,21 @@ def test_multipart_upload_should_return_part_10000():
     part_nrs.should.equal([1, 2, 10000])
 
 
+@mock_s3
+def test_multipart_upload_without_parts():
+    bucket = "dummybucket"
+    s3_client = boto3.client("s3", "us-east-1")
+
+    key = "test_file"
+    s3_client.create_bucket(Bucket=bucket)
+
+    mpu = s3_client.create_multipart_upload(Bucket=bucket, Key=key)
+    mpu_id = mpu["UploadId"]
+
+    list_parts_result = s3_client.list_parts(Bucket=bucket, Key=key, UploadId=mpu_id)
+    list_parts_result["IsTruncated"].should.equal(False)
+
+
 @mock_s3
 @pytest.mark.parametrize("part_nr", [10001, 10002, 20000])
 def test_s3_multipart_upload_cannot_upload_part_over_10000(part_nr):