diff --git a/moto/ec2/models.py b/moto/ec2/models.py
index 08b4e3588..73b630146 100644
--- a/moto/ec2/models.py
+++ b/moto/ec2/models.py
@@ -5610,6 +5610,7 @@ class ManagedPrefixListBackend(object):
         result = managed_prefix_lists
         if filters:
             result = filter_resources(managed_prefix_lists, filters, attr_pairs)
+            result = describe_tag_filter(filters, managed_prefix_lists)
 
         for item in result.copy():
             if not item.delete_counter:
diff --git a/tests/test_ec2/test_prefix_lists.py b/tests/test_ec2/test_prefix_lists.py
index e145f57cb..9c3cb495d 100644
--- a/tests/test_ec2/test_prefix_lists.py
+++ b/tests/test_ec2/test_prefix_lists.py
@@ -76,6 +76,34 @@ def test_describe_managed_prefix_lists_with_prefix():
         lists_by_id[0]["OwnerId"].should.equal("aws")
 
 
+@mock_ec2
+def test_describe_managed_prefix_lists_with_tags():
+    ec2 = boto3.client("ec2", region_name="us-west-1")
+
+    untagged_prefix_list = ec2.create_managed_prefix_list(
+        PrefixListName="examplelist", MaxEntries=2, AddressFamily="?"
+    )
+    untagged_pl_id = untagged_prefix_list["PrefixList"]["PrefixListId"]
+    tagged_prefix_list = ec2.create_managed_prefix_list(
+        PrefixListName="examplelist",
+        MaxEntries=2,
+        AddressFamily="?",
+        TagSpecifications=[
+            {
+                "ResourceType": "prefix-list",
+                "Tags": [{"Key": "key", "Value": "value"},],
+            },
+        ],
+    )
+    tagged_pl_id = tagged_prefix_list["PrefixList"]["PrefixListId"]
+
+    tagged_lists = ec2.describe_managed_prefix_lists(
+        Filters=[{"Name": "tag:key", "Values": ["value"]}]
+    )["PrefixLists"]
+    [pl["PrefixListId"] for pl in tagged_lists].should.contain(tagged_pl_id)
+    [pl["PrefixListId"] for pl in tagged_lists].should_not.contain(untagged_pl_id)
+
+
 @mock_ec2
 def test_get_managed_prefix_list_entries():
     ec2 = boto3.client("ec2", region_name="us-west-1")