diff --git a/moto/route53/responses.py b/moto/route53/responses.py
index 2639caa0c..31c69cbf6 100644
--- a/moto/route53/responses.py
+++ b/moto/route53/responses.py
@@ -113,6 +113,14 @@ def health_check_response(request, full_url, headers):
         health_checks = route53_backend.get_health_checks()
         return 200, headers, template.render(health_checks=health_checks)
 
+def not_implemented_methods(request, full_url, headers):
+    action = ''
+    if 'tags' in full_url:
+        action = 'tags'
+    elif 'trafficpolicyinstances' in full_url:
+        action = 'policies'
+    raise NotImplementedError("The action for {0} has not been implemented for route 53".format(action))
+
 
 LIST_RRSET_REPONSE = """<ListResourceRecordSetsResponse xmlns="https://route53.amazonaws.com/doc/2012-12-12/">
    <ResourceRecordSets>
diff --git a/moto/route53/urls.py b/moto/route53/urls.py
index 69f776ff0..e0c620b6a 100644
--- a/moto/route53/urls.py
+++ b/moto/route53/urls.py
@@ -10,4 +10,5 @@ url_paths = {
     '{0}hostedzone/[^/]+$': responses.get_or_delete_hostzone_response,
     '{0}hostedzone/[^/]+/rrset$': responses.rrset_response,
     '{0}healthcheck': responses.health_check_response,
+    '{0}tags|trafficpolicyinstances/*': responses.not_implemented,
 }