diff --git a/moto/server.py b/moto/server.py
index fcc91ac6c..b028f62bc 100644
--- a/moto/server.py
+++ b/moto/server.py
@@ -62,8 +62,14 @@ class DomainDispatcherApplication(object):
             except ValueError:
                 region = 'us-east-1'
                 service = 's3'
-            host = "{service}.{region}.amazonaws.com".format(
-                service=service, region=region)
+            if service == 'dynamodb':
+                dynamo_api_version = environ['HTTP_X_AMZ_TARGET'].split("_")[1].split(".")[0]
+                # If Newer API version, use dynamodb2
+                if dynamo_api_version > "20111205":
+                    host = "dynamodb2"
+            else:
+                host = "{service}.{region}.amazonaws.com".format(
+                    service=service, region=region)
 
         with self.lock:
             backend = self.get_backend_for_host(host)