diff --git a/moto/lakeformation/models.py b/moto/lakeformation/models.py
index 18cd77abb..b5141dad4 100644
--- a/moto/lakeformation/models.py
+++ b/moto/lakeformation/models.py
@@ -56,6 +56,8 @@ class LakeFormationBackend(BaseBackend):
         return self.resources[resource_arn]
 
     def deregister_resource(self, resource_arn: str) -> None:
+        if resource_arn not in self.resources:
+            raise EntityNotFound
         del self.resources[resource_arn]
 
     def register_resource(self, resource_arn: str, role_arn: str) -> None:
diff --git a/tests/test_lakeformation/test_lakeformation.py b/tests/test_lakeformation/test_lakeformation.py
index bd496734d..69ad2d68e 100644
--- a/tests/test_lakeformation/test_lakeformation.py
+++ b/tests/test_lakeformation/test_lakeformation.py
@@ -41,6 +41,11 @@ def test_deregister_resource():
     err = exc.value.response["Error"]
     assert err["Code"] == "EntityNotFoundException"
 
+    with pytest.raises(ClientError) as exc:
+        client.deregister_resource(ResourceArn="some arn")
+    err = exc.value.response["Error"]
+    assert err["Code"] == "EntityNotFoundException"
+
 
 @mock_lakeformation
 def test_list_resources():