diff --git a/moto/ec2/urls.py b/moto/ec2/urls.py
index b83a9e950..4d85b2f56 100644
--- a/moto/ec2/urls.py
+++ b/moto/ec2/urls.py
@@ -2,6 +2,6 @@ from __future__ import unicode_literals
 from .responses import EC2Response
 
 
-url_bases = ["https?://ec2.(.+).amazonaws.com(|.cn)"]
+url_bases = ["https?://ec2\.(.+)\.amazonaws\.com(|\.cn)"]
 
 url_paths = {"{0}/": EC2Response.dispatch}
diff --git a/moto/ec2_instance_connect/urls.py b/moto/ec2_instance_connect/urls.py
index 829a2145b..e7078264f 100644
--- a/moto/ec2_instance_connect/urls.py
+++ b/moto/ec2_instance_connect/urls.py
@@ -1,6 +1,6 @@
 from __future__ import unicode_literals
 from .responses import Ec2InstanceConnectResponse
 
-url_bases = ["https?://ec2-instance-connect.(.+).amazonaws.com"]
+url_bases = ["https?://ec2-instance-connect\.(.+)\.amazonaws\.com"]
 
 url_paths = {"{0}/$": Ec2InstanceConnectResponse.dispatch}